LI Naa, LI Jia-yanga, KONG Yana, ZHOU Zhen-yua, REN Xiao-liangb, WANG Menga*
a. State Key Laboratory of Component-based Chinese Medicine; b. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Abstract：Sponge, a kind of reticular porous solid agent with the characteristics of strong absorption capacity, light weight and low density, can be used to assist hemostasis, treat trauma, and improve the therapeutic effect with loading drugs. Due to its loose porous structure, strong liquid absorption capacity and good gas permeability, solid sponge is widely applied to wound hemostasis with unique advantages.The solid sponge, which is made of bioactive natural polymer materials such as Bletilla striata polysaccharide and chitosan, can also promote healing and exert antibacterial effects. More importantly,as a drug delivery carrier, solid sponge has been paid more attention. In sum, solid sponge has great potential in hemostasis, wound repair, tissue engineering, drug delivery, as well as its own pharmacological activities.However, the systematic research on solid sponge has not been reported. Therefore, this paper will start from the matrix materials of solid sponge, focusing on its hemostatic and other functional development, the existing evaluation index and performance influencing factors of solid sponge, so as to provide a certain reference for the development of solid sponge.
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2021, Vol. 56 
