Advances in Peptide-Modified pH-sensitive Liposomes
YU Ping-hua1, LIANG Ju1*, ZHAO Huan-le1, LONG Deng-gao2
1. Chemical Engineering and Pharmaceutics School, Henan University of Science and Technology, Luoyang 471023, China; 2. The 16th Middle School of Yiyang City, Yiyang 413064, China
Abstract��As one of drug or gene carriers, peptide-modified pH-sensitive liposomes can actively target the tumor tissues, release anti-tumor drugs in specific areas, reduce side effects of drugs, and improve their therapeutic potency. In this review, the modification methods of peptide-modified liposomes and their anti-tumor applications by gene transfection and drug delivery are introduced. This paper is expected to provide a reference for the preparation of peptide-modified pH-sensitive liposomes and design of carriers for anti-tumor drugs.
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2018, Vol. 53 
