中图分类号:
R944. 1
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参考文献
[1] HAUSSECKER D. Current issues of RNAi therapeutics delivery and development[J] . J Controlled Release, 2014, 195:49-54.
[2] OZPOLAT B, SOOD A K, LOPEZ-BERESTEIN G. Liposomal siRNA nanocarriers for cancer therapy[J] . Adv Drug Deliv Rev, 2014, 66(1):110-116.
[3] CHAKRABORTY C. Potentiality of small interfering RNAs (siRNA) as recent therapeutic targets for gene-silencing[J] . Curr Drug Targets, 2007, 8(3):469-482.
[4] HOERTER J A, WALTER N G. Chemical modification resolves the asymmetry of siRNA strand degradation in human blood serum[J] . RNA,2007, 13(11):1887-1893.
[5] LU J J, LANGER R, CHEN J. A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery[J] . Mol Pharm, 2009, 6(3):763-771.
[6] DASS C R, CHOONG P F M. Selective gene delivery for cancer therapy using cationic liposomes:in vivo proof of applicability[J] . J Controlled Release, 2006, 113(2):155-163.
[7] WANG T, UPPONI J R, TORCHILIN V P. Design of multifunctional non-viral gene vectors to overcome physiological barriers: dilemmas and strategies[J] . Int J Pharm, 2012, 427(1):3-20.
[8] REMAUT K, LUCAS B, BRAECKMANS K, et al. Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides[J] . J Controlled Release, 2007, 117(2):256-266.
[9] ZHANG D, XU H, HU M N, et al. "PEG dilemma" for liposomes and its solving approaches[J] . Acta Pharm Sin (药学学报), 2015, 50(3):252-260.
[10] WANG C H, HSIUE G H. Synthesis and characterization of temperature-and pH-sensitive hydrogels based on poly(2-ethyl-2-oxazoline) and poly(D,L-lactide)[J] . J Polym Sci:Part A:Polym Chem, 2002, 40(8):1112-1121.
[11] YUE H X, WANG X C, XU H. Synthesis and application of 2-oxazoline polymer in drug delivery systems:a review[J] . Chin Pharm J (中国药学杂志), 2017, 52(9):713-720.
[12] VIEGAS T X, BENTLEY M D, HARRIS J M, et al. Polyoxazoline:chemistry, properties, and applications in drug delivery[J] . Bioconju Chem, 2011, 22(5):976-986.
[13] XU H, ZHANG W, LI Y, et al. The bifunctional liposomes constructed by poly(2-ethyl-oxazoline)-cholesteryl methyl carbonate:an effectual approach to enhance liposomal circulation time, pH-sensitivity and endosomal escape[J] . Pharm Res, 2014, 31(11):3038-3050.
[14] XU H, HU M N, YU X, et al. Design and evaluation of pH-sensitive liposomes constructed by poly(2-ethyl-2-oxazoline)-cholesterol hemisuccinate for doxorubicin delivery[J] . Eur J Pharm Biopharm, 2015, 91:66-74.
[15] ZHANG D, LI J Y, WANG X C, et al. Preparation and evaluation of doxorubicin hydrochloride liposomes modified by poly(2-ethyl-2-oxazoline)-cholesteryl methyl carbonate[J] . Acta Pharm Sin (药学学报), 2015, 50(9):1174-1179.
[16] ZHANG Y, LI H M, SUN J, et al. DC-Chol/DOPE cationic liposomes: a comparative study of the influence factors on plasmid pDNA and siRNA gene delivery[J] . Int J Pharm, 2010, 390(2):198-207.
[17] KIM H K, DAVAA E, MYUNG C S, et al. Enhanced siRNA delivery using cationic liposomes with new polyarginine-conjugated PEG-lipid[J] . Int J Pharm, 2010, 392(1):141-147.
[18] YANG S Y, CHEN X J. Advance in the research of cationic liposome carriers for gene delivery[J] . Chin J New Drug (中国新药杂志), 2010, 19(20):1866-1870.
[19] YANG Y F, XIE X Y, YANG Y, et al. A review on the influences of size and surface charge of liposome on its targeted drug delivery in vivo[J] . Acta Pharm Sin (药学学报), 2013, 48(11):1644-1650.
[20] YANG Y F, XIE X Y, YANG Y, et al. A review on the influences of size and surface charge of liposome on its targeted drug delivery in vivo[J] . Acta Pharm Sin(药学学报), 2013, 48(11):1644-1650.
[21] TAGALAKIS A D, LEE D H D, BIENEMANN A S, et al. Multifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA delivery[J] . Biomaterials, 2014, 35(29):8406-8415.
[22] NGUYEN L T, ATOBE K, BARICHELLO J M, et al. Complex formation with plasmid DNA increases the cytotoxicity of cationic liposomes[J] . Biol Pharm Bull, 2007, 30(4):751-757.
[23] LV H T, ZHANG S B, WANG B, et al. Toxicity of cationic lipids and cationic polymers in gene delivery[J] . J Controlled Release, 2006, 114(1):100-109.
[24] ZHI D F, WANG B, CUI S H, et al. Comparison of two kinds of cationic vectors-mediated gene delivery[J] . Acta Pharm Sin (药学学报), 2009, 44(5):553-557.
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脚注
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基金
国家自然科学基金项目资助(81102394);辽宁省自然科学基金项目资助(20170540575)
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