Analysis on the Rationality of Aspirin in Inpatients with Diabetes
CHEN Zhe1, JI Li-wei2, XIE Xiao-hui1*
1. School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; 2. Department of Pharmacy, Beijing Hospital National Medical Center, Beijing 100730, China
Abstract��OBJECTIVE To investigate the use of aspirin in patients hospitalized in department of endocrinology from October 1st, 2015 to March 31th, 2016 and analyze the rationality use of aspirin to promote the proper use. METHODS The appropriateness of aspirin use was analyzed according to relevant guidelines, literature etc. And the safety was analyzed through observing the incidence of adverse drug reaction(ADR). RESULTS The 204 patients were included. For patients with cardiovascular disease or with high cardiovascular risk, aspirin should be used according to guidelines. But the actual utilization rate of aspirin was 62.50% in these two kinds of patients. About 23% of patients used aspirin after a meal which should be used on an empty stomach based on instruction. Although these patients used some drugs that could interact with aspirin, no adverse events observed during hospitalization. For inpatients who used aspirin, the proportion of ADR was only 1.83%. CONCLUSION Rational use of aspirin need to be further improved, the safety of 100 mg aspirin is good.
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CHEN Zhe, JI Li-wei, XIE Xiao-hui. Analysis on the Rationality of Aspirin in Inpatients with Diabetes. Chinese Pharmaceutical Journal, 2018, 53(3): 234-238.
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