SI Jin-guang1,2, ZHANG Tao2, LI Ling-yu2, WANG Meng-hua2, ZOU Zhong-mei2*
1. Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China; 2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Abstract��OBJECTIVE To study the chemical constituents from Periplaneta americana. METHODS The 95% enthanol extract was isolated and purified by column chromatography on silica gel, Sephadex LH-20, ODS and semi-PHPLC. All compounds were identified by chemical and spectral analyses. RESULTS Fourteen compounds were isolated and purified from Periplaneta americana. Their structures were elucidated as salicylic acid (1), benzoic acid (2), phenylacetic acid (3), methyl 4-hydroxyphenylacetate (4), p-hydroxybenzoic acid (5), genistein (6), 3-hydroxybenzoic acid (7), methyl N-(2-hydroxybenzoyl) glycinate (8), 2,5-dihydroxybenzoic acid (9), (2-hydroxybenzoyl) glycine (10), uracil (11), cyclo(Val-Ala) (12), N-acetyldopamine (13), and cyclo(L-Pro-L-Tyr) (14), respectively. CONCLUSION Compounds 2, 4, 7-10, 12 and 14 are obtained from this genus for the first time.
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SI Jin-guang, ZHANG Tao, LI Ling-yu, WANG Meng-hua, ZOU Zhong-mei. Chemical Constituents from Periplaneta americana. Chinese Pharmaceutical Journal, 2018, 53(3): 178-181.
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2018, Vol. 53 
