Abstract��OBJECTIVE To investigate the differences in the accumulation and biosynthesis of metabolites in different lactic acid of Pseudostellariae Radix. METHODS1H-NMR based metabolomic approach combined with multivariate statistical analysis was used to investigate the chemical compositions and find the different metabolites in cultivated Pseudostellariae Radix and its wild-type. RESULTS Thirty-five metabolites were identified in the 1H-NMR spectra, and 15 of which showed remarkable differences. The multivariate statistical analysis showed that the cultivated Pseudostellariae Radix and its wild-type could be distinguished obviously. The contents of isoleucine, linolenic acid, lactic acid, alanine, lysine, glutamic acid, glutamine, acetoacetic acid, succinic acid, ��-aminobutyric acid, phenylalanine, and sucrose in cultivated Pseudostellaria heterophylla were lower than its wild-type, while the cultivated Pseudostellariae Radix contained more xylose, raffinose, and fumaric acid. CONCLUSION This study will provide basic information for exploring the quality formation mechanism and revealing the accumulation and biosynthesis of metabolites in different ecotypes of Pseudostellariae Radix.
�����, ���, ��ʤ��, ����˼, ��ѵ��, ��Ρ, ����Զ, ������. ����1H-NMR��л��ѧ������Ұ��������̫�Ӳλ�ѧ�ɷַ���[J]. �й�ҩѧ��־, 2017, 52(4): 272-276.
HUA Yu-jiao, HOU Ya, WANG Sheng-nan, ZOU Li-si, LIU Xun-hong, GU Wei, LUO Yi-yuan, LIU Juan-xiu. 1H-NMR Based Metabolomic Analysis of Chemical Compositions in Cultivated and Wild Pseudostellariae Radix. Chinese Pharmaceutical Journal, 2017, 52(4): 272-276.
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2017, Vol. 52 
