炎症、胰岛素抵抗与糖尿病的中药治疗

聂绪强,张丹丹,张涵

中国药学杂志 ›› 2017, Vol. 52 ›› Issue (1) : 1-7.

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中国药学杂志 ›› 2017, Vol. 52 ›› Issue (1) : 1-7. DOI: 10.11669/cpj.2017.01.001
综述

炎症、胰岛素抵抗与糖尿病的中药治疗

  • 聂绪强,张丹丹,张涵
作者信息 +

Inflammation, Insulin Resistance and Traditional Chinese Medicine Treatment of Diabetes Mellitus

  • NIE Xu-qiang,ZHANG Dan-dan, ZHANG Han
Author information +
文章历史 +

摘要

现在越来越多的证据表明低度炎症与心脏病,2型糖尿病,阿尔茨海默病以及一些癌症相关。胰岛素抵抗和胰岛素分泌不足是糖尿病发病的两个关键因素,而炎症因子可引起胰岛素抵抗、胰岛素分泌不足。近来研究表明,中药的复方、单体或者提取物对糖尿病、胰岛素抵抗及其炎症也有独特的作用。笔者对炎症、胰岛素抵抗的致病机理及糖尿病的中药治疗做一综述。

Abstract

Low grade inflammation has recently emerged as a common underlying cause of many chronic diseases. Heart disease, type 2 diabetes, Alzheimer′s disease and many types of cancer have all been associated with chronic inflammation. Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Insulin resistance is a key component in the development of diabetes mellitus which is caused by inflammation, and throughout the whole process of diabetes. In recent years, research on traditional Chinese medicine treatment of diabetes has got lots of achievements, and makes a further analysis about insulin resistance of diabetic, while has profound significance in the treatment of diabetes in the future. Insulin resistance can be improved with Chinese herb medicine using compound, single herbal drug and its extracts. This review focuses on the pathogenesis of inflammation and insulin resistance, and the effects of Chinese herb medicine on insulin resistance in diabetes.

关键词

炎症 / 胰岛素抵抗 / 糖尿病 / 中药

Key words

inflammation / insulin resistance / diabetes mellitus / traditional Chinese medicine

引用本文

导出引用
聂绪强,张丹丹,张涵. 炎症、胰岛素抵抗与糖尿病的中药治疗[J]. 中国药学杂志, 2017, 52(1): 1-7 https://doi.org/10.11669/cpj.2017.01.001
NIE Xu-qiang,ZHANG Dan-dan, ZHANG Han. Inflammation, Insulin Resistance and Traditional Chinese Medicine Treatment of Diabetes Mellitus[J]. Chinese Pharmaceutical Journal, 2017, 52(1): 1-7 https://doi.org/10.11669/cpj.2017.01.001
中图分类号: R965   

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基金

国家自然科学基金资助项目(81560712);贵州省科技重大专项(黔科合重大专项字6010);贵州省科技厅联合基金项目(黔科合LH字7566);贵州省教育厅自然科学研究项目(黔教合KY字439);遵义市红花岗区科技项目(遵红科合社字06)
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