目的：研究制备中药少腹逐瘀颗粒剂的工艺。方法：用正交试验设计优化提取条件。以收膏率和HPLC测定浸膏中芍药苷含量为指标，采用二因素（煎煮时间和加水倍数）、三水平进行煎煮条件的选择。结果：优选出的煎煮条件为A₁B₁即：第一次加15倍量水，煎煮1．5h，第二次加10倍量水，煎煮1h。结论：工艺合理，质量稳定，适合于工业生产。

OBJECTIVE: To study the preparation technique of Shaofu Zhuyu granules (preparation of traditional Chinese medicine). METHOD: The optimal extractive factors were found with orthogonal experiment design with table Lg (3⁴). The indexes were the extraction recovery rate and the content of the paeoniflorin determined by HPLC. RESULTS: The optimal extract technique was boiling two times. The first, boiling 1.5 h, adding 15 times content water. The second, boiling 1 h, adding 10 times water. CONCLUSION: The technique is reasonable and it is suitable for industry production of Shaofu Zhuyu granales.