1.Institute of Chinese Materia Medica,Chinese Academy of Traditional Chinese Medicine,Beijing 100700,China;2.College of Science and Technology,Nihon University shiyoda-kv,Tokyo 101,Japan
Abstract��
OBJECTIVE To study the chemical constituents of unsaponifiable lipids from the seeds of Trichosanthes kirilowii Maxim.in order to establish quality standards for Fructus Trichosanthis and Semen Trichosanthis. METHODS The fatty oil was extracted from the seeds of Trichosanthes kirilowii Maxim by ether,the saponification reaction was done with potassium hydroxide.The unsaponifiable lipids were isolated and purified by using silica gel column chromatography.The structures of their constituentes were elucidated by means of IR,MS, 1H-NMR, 13C-NMR and authentic speimens. RESULT 10-��--Cucurbitadienol,karounidiol,isokarounidiol,7-oxodihydrokarounidiol,stigmast-7-en-3-��--ol,stigmast-7,22-dien-3-��--ol,and stigmasta-7,22-dien-3-O--��--D-glucoside were elucidated. CONCLUSION The preceding four compounds were reported for the first time in China.
.Studies on the chemical constituents of unsaponifiable lipids from the seeds of Trichosanthes kirilowii[J] Chinese Pharmaceutical Journal, 2000,V35(11): 733-736
2000, Vol. 35 
