目的 研究当归\[Angelica Sinensis (Oliv.) Diels\]的大极性化学成分。方法 应用多种色谱方法进行分离纯化，通过1H-NMR、13C-NMR等波谱技术确定化合物的结构。结果 分离得到9个化合物，分别鉴定为反式阿魏酸（trans-ferulic acid, 1），顺式阿魏酸（cis-ferulic acid, 2），川芎内酯Ⅰ（senkyunolide Ⅰ, 3），布雷菌素A（brefeldin A, 4），五加苷B1（eleutheroside B1, 5），E-松柏苷（E-coniferin, 6），愈创木基丙三醇（guaiacylglycerol, 7），淫羊藿次苷F2（icariside F2, 8）, 马鞭草烯酮-5-O-β-D-葡萄糖苷（verbenone-5-O-β-D-glucopyranoside，9）。结论 化合物5～9均为首次从该属植物中分离得到。
Abstract
OBJECTIVE To investigate the water-soluble constituents of the root of Angelica sinensis (Oliv.) Diels. METHODS The chemical constituents were isolated by various chromatography techniques, and structurally elucidated by spectral evidence together with physiochemical analysis. RESULTS Nine compounds were isolated from the water extract of Angelica sinensis, and their structures were identified as trans-ferulic acid (1), cis-ferulic acid (2), senkyunolide I (3), brefeldin A (4), eleutheroside B1 (5), E-coniferin (6), guaiacylglycerol (7), icariside F2 (8) and verbenone-5-O-β-D-glucopyranosid (9). CONCLUSION Compounds 5-9 were isolated from Angelica sinensis for the first time.
关键词
当归 /
化学成分
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Key words
KEY WORDS: Angelica sinensis /
chemical constituents
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参考文献
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