[1] DONG J, CHEN X J, SONG J, et al. Pharmacokinetics and enterohepatic cycling of atorvastatin in rat[J]. J China Pharm Univ( 中国药科大学学报 ) , 2008, 39(1):55-59.
[2] CHEN Y J, HUANG S M, LIU C Y, et al. Hepatobiliary excretion and enterohepatic circulation of colchicine in rats[J]. Int J Pharm, 2008, 350(1-2): 230-239.
[3] VIVO R P, KRIM S R, PEREZ J, et al. Digoxin: current use and approach to toxicity[J]. Am J Med Sci, 2008, 336(5):423- 428.
[4] HOUGHTON B L , BOWERS J B . Valproic acid overdose: a case report and review of therapy[J]. Med Gen Med , 2003, 5(1):5.
[5] WU S W, CHANG H R, LAI Y R, et al. Non-life-threatening leukopenia in a renal transplant recipient with acute overdose of mycophenolate mofetil[J]. Transplant Proc , 2008, 40(10):3770-3771.
[6] HASSIKOU H, HAOURI M E, TABACHE F, et al. Le?unomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis[J]. Joint Bone Spine, 2008, 75(5):597-599.
[7] BOLT H M. Interactions between clinically used drugs and oral contraceptives[J]. Environ Health Perspect , 1994, 102(9):35-38.
[8] MESHAL M A , SAYEDY M , BALLA S R , et al. The effect of colestipol and cholestyramine on ibuprofen bioavailability in man[J]. Biopharm Drug Dispos , 1994, 15(6):463-471.
[9] BORROWWS R , CHUSNEY G , LOUCAIDOU M , et al. The magnitude and time course of changes in mycophenolic acid 12-hour predose levels during antibiotic therapy in mycophenolate mofetil-based renal transplantation[J]. <>Ther Drug Monit, 2007, 29(1): 122-126.
[10] KOJIMA S , NADAI M , KITAICHI K , et al. Possible mechanism by which the carbapenem antibiotic panipenem decreases the concentration of valproic acid in plasma in rat[J]. Antimicrob Agents Chemother, 1998, 42(12): 3136-3140.
[11] XING J, CHEN X Y, ZHONG D F . Absorption and enterohepatic circulation of baicalin in rats[J]. Life Sci, 2005,78 (2):140-146.
[12] CHE Q M, CHEN Y, YANG L. Effect of amoxicillin on baicalin level in rat plasma [J]. Chin Pharm J( 中国药学杂志 ), 2007, 42(17): 1340-1342.
[13] CHE Q M, CHEN Y, SONG H. Effect of acetylspiramycin on plasma concentration of baicalin in rat[J]. Chin J New Drugs( 中国新药杂志 ), 2006, 15(17): 1450-1452.
[14] MA Y, LI P B, CHEN D W, et al. LC/MS/MS Quantitation assay for pharmacokinetics of naringenin and double peaks phenomenon in rats plasma[J]. Int J Pharm, 2006, 307 (2):292-299.
[15] DICKINSON B D, ALTMAN R D, NIELSEN N H, et al. Drug interactions between oral contraceptives and antibiotics[J]. Obstet Gynecol, 2001, 98(5): 853-860.
[16] OSBORNE N G. Antibiotics and oral contraceptives: potential interactions[J]. J Gynecol Surg ,2002,18(4):171-172.
[17] DIRK R J K, GEERT V, MAARTEN N, et al. Drug interaction between mycophenolate mofetil and rifampin: Possible induction of uridine diphosphate-glucuronosyltransferase[J]. Clin Pharmacol Ther, 2005, 78(1): 81-88.
[18] SCOTT C A, KELLY L C. Pharmacokinetic drug interactions of morphine, codeine, and their derivatives: theory and clinical reality, part II[J]. Psychosomatics, 2003, 44(6): 515-520.
[19] FANG P F, TANG F C, ZHAO X Y, <>et al. Craft of framework sustained-release tablets of potassium iodine[J]. Cent South Pharm （中南药学） , 2004, 2(3): 156-159.
[20] XIAO P, YU J, ZHANG Y D, <>et al. Experimental study to remove
lead by bioadhesive preparation of activated carbon [J]. Chin J Mod Med( 中国现代医学杂志 ), 2006, 16(14): 2094-2095.
[21] XIAO P, ZHANG Y D, FANG P F. Absorbent removing lead and its effect on trace elements in lead-intoxicated SD rats[J]. Chin J Mod Med( 中国现代医学杂志 ),2006, 16(12): 1779-1785.
[22] KIMURA Y, NAGATA Y, BUDDINGTON R K. Some dietary fibers increase elimination of orally administered polychlorinated biphenyls but not that of retinol in mice[J]. J Nutr, 2004, 134(1):135-142.
[23] MEIJER L, HAFKAMP A M, BOSMAN W E, et al. Nonabsorbable dietary fat enhances disposal of 2,2′,4,4′-tetrabromodiphenyl ether in rats through interruption of enterohepatic circulation[J]. J Agric Food Chem, 2006, 54(17):6440-6444.
[24] JANDACEK O J, ANDERSON N, LIU M, et al. Effects of yo-yo diet, caloric restriction, and olestra on tissue distribution of hexachloro-benzene[J]. Am J Physiol Gastrointest Liver Physiol, 2005, 288(2): 292-299.
[25] JANDACK R J, TSO P. Enterohepatic circulation of organochlorine compounds: a site for nutritional intervention[J]. J Nutr Biochemy, 2007, 18(3):163-167.
[26] REDGRAVE T G, P WALLACE, JANDACK R J, et al. Treatment with a dietary fat substitute decreased Arochlor 1254 contamination in an obese diabetic male[J]. J Nutr Biochemy, 2005, 16(6): 383-384.
[27] URANO T, IWASAKI A, HIMENO S, et al. Absorption of methyl-mercury compounds from rat intestine[J]. Toxicology, 1990, 50(2-3): 159-164.
[28] VERONIQUE C, ELISABETH D, MONIQUE R, et al. Decreased expression of g-glutamyltranspeptidase in the intestinal cell line caco-2 by inducers of cytochrome P4501A1[J]. Biochem Pharmacol , 1998, 56(7): 817-823.
[29] GUO Y J, KANG Z C, ZHANG J J, et al. Effects of flavones and flavonols on CYP1A1 mRNA expression in HepG2 cells [J]. Chin J Lab Diagn （中国实验诊断学杂志） , 2008, 12(8): 952-955.
[30] BAYS H E, GOLDBERG R B. The ‘forgotten’ bile acid sequestrants: Is now a good time to remember?[J]. Am J Ther, 2007, 14(6): 567-580.
[31] CORSINI A , WINDLER E , FARNIER M . Colesevelam hydrochloride: usefulness of a specifically engineered bile acid sequestrant for lowering LDL-cholesterol[J]. Eur J Cardiovasc Prev Rehabil, 2009, 16(1):1-9.
[32] TAKEUCHI A , SANO N , TAKIKAWA H . Inhibition of ileal bile acid absorption by colestimide[J]. J Gastroen Hepatol , 2003, 18(5): 548-553.
[33] FLORENTIN M, LIBERPOULOUS E N, MIKHAILIDIS D P, et al. Colesevelam hydrochloride in clinical practice: a new approach in the treatment of hyper-cholesterolemia[J]. Curr Med Res Opin, 2008, 24(4): 995-1009.
[34] YAMAKAWA T , TAKANO T , UTSUNOMIYA H , et al. Effect of colestimide therapy for glycemic control in type 2 diabetes mellitus with hyper- cholesterolemia[J]. Endocr J, 2007, 54(1): 53-58.
[35] UEGAKI S , TANAKA A , MORI Y , et al. Successful treatment with colestimide for a bout of cholestasis in a japanese patient with benign recurrent intrahepatic cholestasis caused by ATP8B1 cutation[J]. Inter Med , 2008, 47 (7) : 599-602.
[36] VICENS M, MACIAS R I, BRIZ O , et al. Inhibition of the intestinal absorption of bile acids using cationic derivatives: Mechanism and repercussions[J]. Biochem Pharmacol, 2007, 73(3):394-404.
[37] KITAYAMA K , NAKAI D , KONO K , et al. Novel non-systemic inhibitor of ileal apical Na⁺-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys[J]. Eur J Pharmacol , 2006,539(1-2): 89-98.
（ 收稿日期 ： 2009-05-22 ）