线粒体功能障碍与帕金森病

李晓秀;杜冠华

中国药学杂志 ›› 2009, Vol. 44 ›› Issue (17) : 1284-1286.

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PDF(1614 KB)
中国药学杂志 ›› 2009, Vol. 44 ›› Issue (17) : 1284-1286.
论文

线粒体功能障碍与帕金森病

  • 李晓秀,杜冠华 *
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文章历史 +

摘要

目的 综述线粒体功能障碍与帕金森病( Parkinson’s disease, PD )关系的研究进展。 方法 依据最新国内外文献,进行归纳总结。 结果与结论 线粒体呼吸链缺陷,线粒体 DNA 异常和线粒体相关基因突变可能直接或间接地参与了 PD 发生和发展。线粒体功能障碍与 PD 密切相关。

关键词

帕金森病 / 线粒体呼吸链 / 线粒体 DNA / 基因突变

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李晓秀;杜冠华 . 线粒体功能障碍与帕金森病[J]. 中国药学杂志, 2009, 44(17): 1284-1286

参考文献


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( 收稿日期 : 2008-10-21 )


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