Caco-2 细胞模型在口服药物转运机制研究中应用的进展

齐云;王敏;蔡润兰

中国药学杂志 ›› 2009, Vol. 44 ›› Issue (17) : 1281-1283.

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中国药学杂志 ›› 2009, Vol. 44 ›› Issue (17) : 1281-1283.
论文

Caco-2 细胞模型在口服药物转运机制研究中应用的进展

  • 齐云,王敏,蔡润兰
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摘要

目的 介绍近年来 Caco-2 细胞模型在口服药物吸收机制的研究进展。 方法 通过对国内外文献的分析与总结,较为全面地介绍了基于 Caco-2 模型进行的口服药物转运机制研究现状及发展趋势。 结果与结论 以研究药物被动转运机制为主的 Caco-2 细胞模型,近年在主动转运机制的研究上有迅猛发展,尤其在双向主动转运研究上越来越受到重视与推崇,这些发展动态值得重视。

关键词

Caco-2 细胞模型 / 药物吸收 / 跨膜转运

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齐云;王敏;蔡润兰 . Caco-2 细胞模型在口服药物转运机制研究中应用的进展[J]. 中国药学杂志, 2009, 44(17): 1281-1283

参考文献


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( 收稿日期 : 2009-02-13 )


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