Studies on Chemical Constituents in Roots of Uraria crinita
hui2,3*
Author information+
(1. First College of Clinical Medical Science of China Three Gorges University & Yichang Central People’s Hospital， Yichang 443003，China；2. Faculty of Pharmaceutical Sciences，Tongji Medical College of Huazhong University of Science and Technology，Wuhan 430030，China；3. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation，Wuhan 430030，China
OBJECTIVE to study chemical constituents in roots of Uraria crinita. METHODS The compounds were isolated by means of column chromatography on sinica gel，DIAION HP20，Sephadex LH-20 and ODS. Their structures were elucidated by physicochemical properties and spectra. RESULTS Fourteen compounds were obtained and identified as β-sitosterol（1），octadecanoic acid（2），palmitic acid（3），β-daucosterol（4），(24R)-stigmast-7，22（E）-dien-3α-ol（5），2-(acetylamino)benzoic acid，methyl ester（6），betulin（7），m-hydroxybenzoic acid（8），5,7-dihydroxy-2'-methoxy-3',4'-methylenedioxyisoflavanone（9），sucrose（10），sophoradiol（11），genistein（12），genistin（13），and silybin(14）. CONCLUSION Compound 5，6，7，8，9，10，11，13，and 14 were isolated from the plant for the first time.
hui;.
Studies on Chemical Constituents in Roots of Uraria crinita[J]. Chinese Pharmaceutical Journal, 2009, 44(16): 1217-1220
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Jahan N ， Ahmed W ， Malik A. New steroidal glycosides from Mimusops elengi [J] . J Nat Prod ， 1995 ， 58 （ 8 ）： 1244-1247. [2] ALAN E. Physical organic chemistry [J]. J Chem Soc ， 1979, （ 8 ）： 1058-1063. [3] GAO H Y ， WU L J ， Chemical constituents of Chaenomeles sinensis ( Thouir ) [J]. Chin J Nat Med （中国天然药物）， 2003 ， 1(2) ： 82 - 84. [4] YU D Q. <>Handbook of Analytical Chemistry （分析化学手册） [M ] . Vol 7.Beijing ： Chemical Industry Press ， 2002 ： 561-758. [5] Rahman M M ， Simon G . Isoflavanones from Uraria picta and their antimicrobial activity [J]. Phytochemistry ， 2007 ， 68(12): 1692-1697. [6] ZHOU J E ， CHEN C Y ， XIE Y F. Studies on liposoluble constituents from fruit of Sophora japonica L [J]. J Shanghai Jiaotong Univ （上海交通大学学报） , 2006 , 26(11):1245 - 1248. [7] Tsanuo M K ， Hassanali A ， Hooper A M ， et al. Isoflavanones from the allelopathic aqueous root exudate of Desmodium uncinatum. [J]. Phytochemistry, 2003, 64 （ 1 ）： 265. [8] VICTOR R F ， Mota-Filipe H ， Teixeira G ， et al . Flavonoids of an extract of Pterospartum tridentatum showing endothelial protection against oxidative injury[J]. Ethnol Pharmacol, 2004, 93 （ 2 ） : 363 - 370. [9] LEE D Y ， Liu Y Z. Molecular structure and stereochemistry of silybin A ， s ilybin B ， i sosilybin A ， and isosilybin B ， isolated from Silybum marianum （ Milk Thistle ） [J]. J Nat Prod, 2003, 66(9): 1171 - 1174. （ 收稿日期 ： 2008-11-04 ）
PDF(2090 KB)
