目的综述HIV-1逆转录酶的二聚化及其抑制剂的研究进展。方法查阅近年相关文献,进行分析评述。结果与结论酶的二聚化是逆转录酶发挥功能所必需的,抑制逆转录酶二聚化成为近年来研究抗HIV药物的一个新的靶点,现已发现的两类二聚化抑制剂为研究新的抗HIV药物提供了基础。
关键词
HIV-1 /
逆转录酶 /
二聚化 /
抑制剂
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参考文献
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脚注
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基金
国家自然基金资助项目(30772629;30371686);国际合作重点项目(2003DF000033)
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