摘要
目的研究萝卜秦艽(Phlomis medicinalis Diels)的化学成分。方法采用大孔树脂、薄层色谱、硅胶柱色谱和制备高效液相色谱,进行分离纯化,通过理化实验和波谱分析的方法进行结构鉴定。结果将体积分数95%乙醇提取物经大孔树脂吸附,再以体积分数10%乙醇洗脱分离、鉴定了7个化合物,分别为:pulchellosideⅠ(Ⅰ),lamalbide(Ⅱ),7-epiphlomiol(Ⅲ),penstemoside(Ⅳ),β-dihydrohastatoside(Ⅴ),phloyosideⅢ(Ⅵ)及decaffeoylacteoside(Ⅶ)。结论所有化合物均为首次从该植物中分得;其中化合物Ⅴ和Ⅶ为首次从该属植物中分得。
Abstract
OBJECTIVE To study the chemical constituents of Phlomis medicinalis Diels.METHODS The compounds were isolated and repeatedly purified by macroporous resin,silica gel column chromatography,TLC and Prep-HPLC.Their structures were elucidated by physical and chemical properties and NMR spectra.RESULTS Seven compounds were obtained and elucidated as pulchellosideⅠ(Ⅰ),lamalbide(Ⅱ),7-epiphlomiol(Ⅲ),penstemoside(Ⅳ),β-dihydrohastatoside(Ⅴ),phloyosideⅢ(Ⅵ),decaffeoylacteoside(Ⅶ).CONCLUSION All the compounds were isolated from the plant for the first time.Compound Ⅴ and Ⅶ were obtain-ed from the Plants of Phlomis for the first time.
关键词
萝卜秦艽 /
化学成分 /
环烯醚萜苷
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Key words
Phlomis medicinalis /
chemical constituents /
iridoid glucosides
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薛恒跃 ;王钢力;李萍;林瑞超.
萝卜秦艽化学成分的研究(Ⅳ)[J]. 中国药学杂志, 2008, 43(10): 739-741
XUE Heng-yue;WNG Gng-li;LI Ping;LIN Rui-cho.
Studies on Chemical Constituents of Phlomis medicinalis(Ⅳ) [J]. Chinese Pharmaceutical Journal, 2008, 43(10): 739-741
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参考文献
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脚注
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