摘要
目的研究毛茛科植物赤药(Paeonia lactiflora Pall.)的化学成分。方法应用色谱技术分离纯化,波谱方法解析结构。结果从赤芍中分离出5个化合物:9-乙基芍药新苷A(1),(1S,2S,4R)-反式-1,8-桉叶素-2-O-(6-O-α-L-鼠李糖基)-β-D-葡萄糖苷(2),(1S,2S,4R)-反式-2-羟基-1,8-桉叶素(3),没食子酸(4),没食子酸乙酯(5)。结论化合物1为新的天然产物,2、3为首次从赤芍中分离得到。
Abstract
OBJECTIVE To study the chemical constituents of Paeonia lactiflora Pall.METHODS The compounds were isolated by various column chromatography and identified by physiochemical properties and spectral analysis.RESULTS Five compounds were isolated and identified as 9-ethyl-neo-paeoniaflorin A(1),(1R,2S,4R)-trans-1,8-cineole-2-O-β-D-glucopyranoside(2),(1S,2S,4R)-trans-2-hydroxy-1,8-cineole(3),gallic acid(4)and ethyl gallate(5).CONCLUSION Compound 1 was new natural compound,and compound 2 and 3 were isolated from this plant for the first time.
关键词
赤芍 /
化学成分 /
单萜
{{custom_keyword}} /
Key words
Paeonia lactiflora Pall. /
chemical constituents /
monoterpene
{{custom_keyword}} /
王彦志;冯卫生;石任兵;刘斌;姜艳艳.
赤芍中的单萜类成分[J]. 中国药学杂志, 2008, 43(09): 669-671
WNG Yn-zhi;FENG Wei-sheng;SHI Ren-ing;LIU in;JING Yn-yn.
Monoterpenes of Paeonia lactiflora Pall [J]. Chinese Pharmaceutical Journal, 2008, 43(09): 669-671
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] WANG Y Z，SHI R B，LIU B. Isolation and structure identification of the chemical constituents from Paeonia lactiflora Pall.[J] . J Beijing Univ Tradi Chin Med(北京中医药大学学报)，2006，29(4)：267-269.
[2] YU D Q，YANG J S. Handbook of Analytical Chemistry(The Seventh Fascicule)(分析化学手册-第七册)[M] .Beijing： Chemistry Industry Press，1999(Volumn 7)：902-904.
[3] MITUO MIYAZAWA，HIROMU. Hydroxycineole：Four new metabolites of 1，8-cineole in rabbits[J] .J Agric Food Chem，1989，37：222-226.
[4] TORU I，JUNICHI K，YASUKO T，et al.Water-soluble constituentsof Fennel.Ⅵ.1，8-cineole type glycosides[J] .Chem Pharm Bull，1998，46(11)： 1738-1741.
[5] ZHANG Q G，TAN W J，CHEN K L. Studies on the chemical constituents of Ampelopsis humulifolia var.heterophylla (Thunb.) k. koch.[J] .J Chin Med Mater(中药材)，2003，26(9)： 636-637.
[6] KANED M，LITAKA Y，SHIBATA S.Chemical studies on the oriental plant drugs-ⅩⅩⅩ Ⅲ[J] .Tetrahedron，1972，28： 4309-4317.
{{custom_fnGroup.title_cn}}
脚注
{{custom_fn.content}}
