目的研究民族药物思茅豆腐柴(Premna szemaoensis Pei)中的黄酮类化学成分。方法利用Sephadex LH-20及硅胶等色谱技术进行分离纯化,根据理化性质、光谱数据进行结构鉴定。结果得到7个黄酮类化合物,分别鉴定为5,4'-二羟基- 3,7,3'-三甲氧基黄酮(1),5-羟基-3',4',6,7-四甲氧基黄酮(2),5,4'-二羟基-7-甲氧基黄酮醇(3),5,3'-二羟基-7,4'-二甲氧基黄酮醇(4),3',4',5-三羟基-3,7-二甲氧基黄酮(5),5,7-二羟基-4'-甲氧基黄酮(6),5-羟基-7,3',4'-三甲氧基黄酮醇(7)。结论这7个化合物均为首次从思茅豆腐柴中分离得到。
Abstract
OBJECTIVE To investigate the chemical constituents of Premna szemaoensis Pei.METHODS The compounds were isolated and purified via silica gel and Sephadex LH-20 column chromatography repeatedly and their structures were elucidated on the basis of spectroscopic evidences and physicochemical properties.RESULTS Seven flavanoids were obtained and identified as 5,4'- dihydroxy -3,7,3'-trimethoxyflavone(1),5-hydroxy-3',4',6,7-tetramethoxyflavone(2),5,4'-dihydroxy-7-methoxyflavonol(3),5, 3'-dihydruxy-7,4'-dimethoxyflavonol(4),3',4',5-trihydroxy-3,7-dimethoxyflavone(5),5,7-dihydroxy-4'-methoxyflavone(6),5- hydroxy-7,3',4'-trimethoxyflavonol(7).CONCLUSION All compounds are isolated from the plant for the first time.
关键词
思茅豆腐柴 /
黄酮 /
黄酮醇
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Key words
Premna szemaoensis Pei /
flavone /
flavonol
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参考文献
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脚注
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