摘要
目的介绍小分子EGFR酪氨酸激酶抑制剂的研究进展,为其深入研究提供参考。方法查阅、总结近几年国内、外有关文献。结果与结论靶向酪氨酸激酶的小分子抑制剂研究有了长足进展。随着小分子酪氨酸激酶抑制剂的作用机制及构效关系研究的不断深入,为该类抑制剂的合理药物设计提供可能,评价更加成熟,在抗肿瘤领域有较为广阔的应用前景。
关键词
受体酪氨酸激酶 /
小分子酪氨酸激酶抑制剂 /
抗肿瘤作用
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何伍;凌霄.
小分子EGFR酪氨酸激酶抑制剂研究进展[J]. 中国药学杂志, 2007, 42(22): 1685-1688
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