碳青霉烯类抗生素结构与活性关系研究进展

郑满结;马淑涛

中国药学杂志 ›› 2007, Vol. 42 ›› Issue (22) : 1681-1685.

中国药学杂志 ›› 2007, Vol. 42 ›› Issue (22) : 1681-1685.
综述

碳青霉烯类抗生素结构与活性关系研究进展

  • 郑满结;马淑涛
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摘要

目的综述碳青霉烯类抗生素的作用机制、结构修饰及抗菌活性等方面的研究现状。方法以近几年国内外有代表性的论文为依据,进行分析、整理和归纳。结果与结论碳青霉烯类抗生素具有优越的抗菌活性,以及良好的β-内酰胺酶稳定性。目前已有若干新碳青霉烯类化合物进入临床研究,具有良好开发前景。

关键词

碳青霉烯 / 抗菌活性 / 杂环 / 结构修饰

引用本文

导出引用
郑满结;马淑涛. 碳青霉烯类抗生素结构与活性关系研究进展[J]. 中国药学杂志, 2007, 42(22): 1681-1685

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基金

国家自然科学基金资助项目(20372043);山东省科技攻关项目(2005GG3202098)

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