抗艾滋病作用新靶点——HIV衣壳蛋白及其抑制剂研究概况

程寿玲;刘立;陈中雷;胡春

中国药学杂志 ›› 2006, Vol. 41 ›› Issue (23) : 1761-1763.

中国药学杂志 ›› 2006, Vol. 41 ›› Issue (23) : 1761-1763.
综述

抗艾滋病作用新靶点——HIV衣壳蛋白及其抑制剂研究概况

  • 程寿玲;刘立;陈中雷;胡春
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摘要

目的综述HIV衣壳蛋白及其抑制剂的研究概况。方法以国内外有代表性的论文为依据,进行分析、整理和归纳。结果与结论HIV衣壳蛋白正在成为一个具有潜在抗病毒作用的靶点,目前已经发现抑制HIV-1衣壳蛋白的化合物CAP-1在体内具有显著的抗病毒作用,化合物PA-457已经成为目前抗艾滋病化合物中唯一一种抑制HIV衣壳蛋白的成熟抑制剂正处于临床研究阶段。

关键词

药物化学 / 人类免疫缺陷病毒 / 衣壳蛋白

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程寿玲;刘立;陈中雷;胡春. 抗艾滋病作用新靶点——HIV衣壳蛋白及其抑制剂研究概况[J]. 中国药学杂志, 2006, 41(23): 1761-1763

参考文献

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