OBJECTIVE To study the chemical constituents of the stem of Akebia trifoliata(Thunb.) Koidz.var.australis(Diels) Rehd. METHODS The compounds were isolated and purified by recrystallization and column chromatography with silica gel and Sephadex LH-20.Their structures were elucidated on the basis of physicochemical properties and spectral analysis.RESULTS Eight compounds were identified as calceolarioside B(Ⅰ),1-O-β-D-(3,4-dihydroxyphenyl)-ethyl-6-O-trans-feruloyl-glucopyranoside(Ⅱ),1-O-β-D-(4-hydroxyphenyl)-ethyl-6-O-trans-caffeoyl-glucopyranoside(Ⅲ),2α,3β-dihydroxyolean-12-en-28-oic acid(Ⅳ),daucosterol(Ⅴ),β-sitosterol(Ⅵ).CONCLUSION All compounds are isolated from Akebia trifoliata(Thunb.) Koidz.var.australis(Diels) Rehd for the first time and compound Ⅰ～Ⅲ are isolated from Akebiae trifoliata plants for the first time.
GO Hui-min;WNG Zhi-min;WNG Ji-ming.
Studies on Chemical Constituents in Stem of Akebia trifoliata var.australis[J]. Chinese Pharmaceutical Journal, 2006, 41(05): 333-334
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] ChP（2005）Vol Ⅱ（中国药典2005年版. 二部）[S] . 2005：43.
[2] MA S C，CJEN D C，ZHAO S J.The study on the constituents of yuzhizioside(Ⅰ)[J] . Chin Tradit Herb Drugs（中草药），1994，25(4)：171-174.
[3] MA S C，CHEN D C，ZHAO S J.The study on the constituents of yuzhizioside(Ⅱ)[J] . Chin Tradit Herb Drugs（中草药），1994，25(11)：613-616.
[4] MA S C，CHEN D C，ZHAO S J.The study on the constituents of yuzhizioside（Ⅲ）[J] . Nat Product R & D（天然产物研究与开发），1996，10（3）：49-51.
[5] MA S C，CHEN D C，ZHAO S J.The study on the constituents of yuzhizioside（Ⅳ）[J] . Chin Tradit Herb Drugs（中草药），1995，26（3）：122-124.
[6] MA S C，CHEN D C，ZHAO S J.The structure of yuzhizioside (Ⅳ) from the seed of Akebia trifoliate[J] . Chin Tradit Herb Drugs（中草药），1993，24(11)：563-566.
[7] DAMTOFT S，JENSEN S R. Three phenylethanoid glucosides of unusual structure from Chirita sinensis(Gesneriaceae)[J] . Phytochemistry，1994，37（2）：441-443.
[8] HIROKO S，YUTAKA S，TOKUO A. Cyanogenic and phenylpropanoid glucosides from Prunus grayana[J] . Phytochemistry，1987，26(8)：2363-2366.
[9] TAYFUN E，DENIZ T，IHSAN C. Phenylethanoid glycosides from Scutellaria galericulata[J] . Turk J Chem，2002，26(4)：465-471.
[10] GUO Q L，YANG J S. Studies on chemical constituents in fruit of Rubus chingii[J] . China J Chin Mater Med（中国中药杂志），2005，30（3）：198-200.
