目的测定盐酸埃他卡林片的含量、含量均匀度及溶出度。方法采用溶剂萃取酸性染料比色法测定含量，检测波长412 nm。溶出度以桨法测定，转速50 r·min^-1，溶出介质为250 mL 0.1 mol·L^-1盐酸溶液。结果1.5～7.5 μg·mL^-1内线性良好，r=0.999 9 (n=3)，平均回收率100.2% (n=10)，RSD为0.5657%。片剂10 min取样，主药溶出80%以上。结论方法简便、准确、专属性强。可作为该制剂的含量测定和质量控制方法。

OBJECTIVE To determine the content and dissolution of Iptakallm Hydrochloride tablets (IHT). METHODS A solvent extractionacid dye spectrophotometry method was used with the detection wavelength at 412 nm.Paddle method was used to determine the dissolution.The rotation speed was 50 r·min^-1 and the dissolution medium was 250 mL of 0.1 mol·L^-1Hydrochloric acid solution. RESULTS The linear range of the standard curve was 1.5～7.5 μg·mL^-1 (r=0.999 9，n=3).The average recovery of the assay was 100.2% with a relative standard deviation of 0.565 7% (n=10).The drug dissolution at 10 min was above 80%. CONCLUSION This method is convenient,accurate and specific for the quality control of IHT.