OBJECTIVE To study the drug-releasing characteristics in vitro of Xianghe medicinal strip. METHODS The content of the index composition was determined by HPLC. Magnetic stirring method was used to study the releasing rule with releasing medium of lactic acid solution (pH 4.5). RESULTS Releasing in vitro of the strip conforms to first order kinetics equation. The accumulative releasing percentage of 2 hours and 12 hours was 61.9% and 94.2%, respectively.CONCLUSIONS The releasing characteristics of Xianghe medicinal strip can be described by two-phase dynamic model.
DENG Yun-Hui;YNG Liu;FENG Yi;et l.
Study on the releasing dynamics in vitro of Xianghe medicinal strip[J]. Chinese Pharmaceutical Journal, 2002, 22(07): 390-391