OBJECTIVE To study the anti-inflammatory and antipruritus effects of Yangan lotion. METHODS The microcirculation of the mouse s auricle was observed.The inflammation was caused by dimethylbenzene and albumen;The itch was caused by histamine and with extrinsis-antisepsis.The MIC in vitro was also determined. RESULTS Yangan lotion improved the microcirculation of the mouses auricle,produced the anti-inflammatory effects on the inflamed ear of the mouse caused by dimethylbenzene and the inflamed gymnoarthrosis of the hamster caused by albumen and relieved itching on the cavys place caused by histamine. CONCLUSION Yangan lotion had the obvious effects on dermatitis pruritus.
YN Xing-lin;WEI Zhong-ling;CHEN i-qun.
Innestigation on the anti-inflammatory and antipruritus effects of Yangan lotion in mice[J]. Chinese Pharmaceutical Journal, 2000, 35(06): 384-385