石斛小菇化学成分的研究

郭顺星 陈晓梅 杨峻山 曹文芩 肖盛元

中国药学杂志 ›› 2000, Vol. 35 ›› Issue (06) : 372-374.

中国药学杂志 ›› 2000, Vol. 35 ›› Issue (06) : 372-374.
中药及天然药物

石斛小菇化学成分的研究

  • 郭顺星,陈晓梅,杨峻山,曹文芩,肖盛元
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Studies on the chemical consitituents of Mycena dendrobii

  • GUO Shun-xing,CHEN Xiao-mei,YANG Jun-shan,CAO Wen qin,XIAO Sheng-yuan
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摘要

目的 研究石斛小菇(Mycena dendrobii Fan et Guo)的化学成分。方法 利用柱色谱法,从石斛小菇中分离出9个化合物,并根据理化性质和光谱技术,对其中的7个化合物进行了结构鉴定。结果 7个化合物分别为D-甘露醇(Ⅰ),尿嘧啶(Ⅱ),黄嘌呤(Ⅲ),5-羟甲基糠醛(Ⅳ),狼毒甲素(Ⅴ),正三十一烷(Ⅵ)和尿素(Ⅶ)。结论 除D-甘露醇外,以上化合物均系首次从小菇属真菌中获得。

Abstract

OBJECTIVE To study the chemical constituents of Mycena dendrobii Fan et Guo. METHODS The constituents were separated and purified by using column chromatgraphy with silica gel.Its structures were determined by IR,1H-NMR, 13C-NMR and MS spectra respectively. RESULTS Nine compounds were isolated and seven of them were identified as D mannitol(Ⅰ),uracil(Ⅱ),xanthine(Ⅲ),5-hydroxymethyl furfuraldehyde(Ⅳ),2-furancarboxaldehyde,5,5-[oxybis(methylene)]bis(Ⅴ),hentriacontane(Ⅵ) and urea(Ⅶ). CONCLUSION It is the first time for these compounds exceptⅠ to be isolated from all the speies of Mycena geners.

关键词

石斛小菇 / 化学成分 / 尿嘧啶 / 黄嘌呤 / 5-羟甲基糠醛

Key words

Mycena dendrobii / chemical constituents / uracil / xanthine / 5-hydroxymethyl furfuraldehyde

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郭顺星 陈晓梅 杨峻山 曹文芩 肖盛元. 石斛小菇化学成分的研究[J]. 中国药学杂志, 2000, 35(06): 372-374
GUO Shun-xing;CHEN Xio-mei;YNG Jun-shn;CO Wen qin;XIO Sheng-yun. Studies on the chemical consitituents of Mycena dendrobii[J]. Chinese Pharmaceutical Journal, 2000, 35(06): 372-374

参考文献

[1]Guo SX,Fan Li,Cao WQ,et al.Mycena dendrobii,a new Myc-orrhizal fungus[J].Mycosystema,1999,18(2):141. [2]赵余庆,袁昌鲁,李铣,等.红毛五加化学成分的研究(Ⅲ)[J].中国中药杂志,1991,16(7):421. [3]余竟光,陈若云,姚志熙.薄盖灵芝深层发酵菌丝体化学成分的研究(Ⅲ)[J].中草药,1983,14(10):438. [4]王明安,陈绍农,张唐迪,等.藏药五脉绿绒蒿化学成分的研究Ⅰ[J].兰州大学学报(自然科学版),1991,27(4):80. [5]RamarosonRaonizafinimanana B,Gaydou EM,Bombarda Ⅰ.Hydrocarbons from three Vanilla Bean Species:V.fragrans,V.madagascariensis and V.tahitensis[J].J Agric Food Chem,1997,45(7):2542.

基金

国家自然科学基金资助项目(39770017)

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