OBJECTIVE: To observe the stabilities of inclusion complex of garlic oil-β-cyclodextrin(β-CD).METHODS: We used garlic oil as a index and made a set of tests of inclusion complex and mixture on their stabilities,such as tests under lamp light and under high temperature or humidity, volatility test and constant-temperature accelerated test. RESULTS: Under affecting factors such as light, heat and humidity, the content of garlic oil in inclusion complex was not changed. In the mixture, however, the content of garlic oil was decreased. It was shown that garlic oil in inclusion complex was much more stable under light, heat and humidity. In the volatility test, hot weightless of the complex was smaller than that of the mixture, indicating that inclusion complex was able to lower volatilization of garlic oil. CONCLUSION: Inclusion complex of garlic oil-β-CD had the stabilities to light, heat and humidity to some extent. The stability of garlic oil in inclusion complex was obviously superior to that of original garlic oil.
He Jin.
The stabilities of inclusion complex of garlic oil-β-cyelodextrin[J]. Chinese Pharmaceutical Journal, 1997, 32(04): 216-218
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