目的:分析多棘蜈蚣(Scolopendra multidens Newport)的化学成分，并与药典收载品少棘娱蚣(S. mutilans L. Koch)比较。方法:采用溶媒提取法测定总脂，气相色谱-质谱-计算机检测脂肪酸，微量凯氏定氮法测定蛋白质. 离子交换色谱测定游离氛基酸，电感祸合离子发射光谱测定微量元素。结果:多棘娱蚣含总脂7.2%，蛋白质646%，游离氛墓酸6.3%;含有与少棘埃蛤相同的15种脂肪酸(其中不饱和脂肪酸占72% ).21种氛玉酸和12种徽量元素。结论:多棘娱蚣与少棘娱蚣主要化学成分类同，某些成分含量存在差异，是一种值得开发利用的药用蜈蚣资源。

OBJECTIVE: To analyse chemical composition of Scolopendra multidens Newport and compare it with S.mutilans L. Koch. METHODS; Lipid was determined by solvent-extraction. GGMS-DS system was used to analyse fat acids. The total protein was determined by the method provided by Chinese Pharmacopoeia ( Appendix IX L.).Ion exchange chromatography was used for the analysis of free amino acids. ICP-AES was used for the analysis of trace elements. RESULTS:The lipid content was 7.2%，protein was 64.6 %，and total free amino acid was 6. 3 %.S multidens contained the same fifteen fat acids (the content of unsaturated fat acids was nearly 72% in its fat ids),twenty one amino acids and twelve trace elements as S .mutilans had. CONCLUSION: S. multidens and S. utilans have the same main chemcal composition. The contents of some compositions are different. S.multidens is worth exploiting as the nature resources of medicinal centepede.