摘要
利用计算机图像处理技术进行动物行为的药理学研究,已成为国标药理学界的发展趋势。为
此.作者在国内首先采用计算机自动控制与图像处理技术,对用于促智药物研究、主要测试动物空间学
习能力的水迷宫进行了改进.通过自行编译的软件程序.将动物在水迷宫中游泳的全过程经摄像后被计
算机识别,变为动物的实时活动轨迹图像在屏幕上进行动态显示.同时提供学刁分数、到达平台时间、进
入盲端错误次数、游泳距离及速度等指标,这样使得有效信量尽可能的多.保证所获的实脸结果更为
科学容观、准确可靠。
Abstract
Using computer-aided control and video-tracking techniques to screen and study new drugs in animals has been forging rapidly. We applied those techniques to develop a computer-aided system for measuring water-maze performance. mainly spatial learning in the rat and mouse. The program utilized the video-tracking capabilities to measure the subject's attempt to search out the goal platform in square water-maze.The software in the system was designed in modularity and programmed with C++ language. The interfaces were designed as user friendly.The functions included,but not limited to:allowing the users to collect data including number of entries into culs de sac (which is scored in terms of number of errors);the latency period to reaching the goal;the learning in-dex (LI = total number of correct responses/total number of correct responses+total number of error responses.) and the swimming speed;providing hardcopy of screen graphics and results by various printers ;data file saving in and loading from hard disk and floppy disks,a unique approach to scientific data analysis.The computer-aided system made information refined as much as possible and guaranteed experimental results more scientific and reasonable.
关键词
计算机自动控制 /
图像分析 /
硬件/软件 /
水迷宫
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Key words
computer-aided control system /
video-tracking technique /
hardware/software /
water-maze
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.陈善广;孟慧;宿双宁
.刘新民;王圣平;尚伟芳;于澍仁;王立为;肖培根.
水迷宫的计算机自动控制与图像分析处理系统[J]. 中国药学杂志, 1995, 30(S1): 21-23
Liu Xinmin;Chen Shngung;Meng Hui;Wng Shengping;Shng Weifng;Yu Shuren;Wng Li-wei;Su Shungning;Xio Peigen.
A computer-aided procedure and tracking technique for measuring water-maze performance[J]. Chinese Pharmaceutical Journal, 1995, 30(S1): 21-23
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参考文献
1 刘新民,王圣平,陈善广,等.小鼠跳台的计算机自动监控系统.中国实验动物学报.1994,1:43.
2刘新民,陈善广,王圣平,等.计算机控制的避暗系统.中国医学科学院学报,1995,(6)(排版中).
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脚注
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