采用中药血清药理学研究方法，对含苦参及仙鹤草血清与中药煎剂体外抗肿瘤活性进行了 比较研究，发现苦参、仙鹤草煎剂及含苦参血清均有明显的抗肿瘤活性，而含仙鹤草血清则无效。初步 证明苦参对肿瘤细胞体外生长确实有一定的细胞毒作用，而含仙鹤草血清及其煎剂出现不同实验结果 的原因，可能与中药粗制剂干扰因素有关，也可能受药物在体内代谢过程及血清等因素的影响。

With the method of serum pharmacology,we studied the antitumor activity of the serum with Sophora flavescens Ait.(SFA) and Agrimonia pilosa Ledeb.(APL)-The results showed that the serum with SFA(S-SFA) could obviously inhibit the proliferation of S₁₈₀and EAC cells in vitro.With the anti-staining method, we found that the S-SFA could inhibit EAC cells growth by 50.2% and the serum with APL(S-APL)by 1.5%;with the MTT assay , we found that when S-SFA was added and cultured with S₁₈₀ and EAC cells for 3 days the percentage of cytotoxicity was 27.78%and 34.58% respectively,but the S-APL had no effect on S₁₈₀ or EAC cells.Thesa experiments suggest that SFA has significant antitumor activity.