Abstract: Objective: To compare the difference effects on the proximal stomach between rapid (intake rate 100ml/min) and slow (intake rate 15ml/min) LNLT. Methods: Forty healthy subjects received both the rapid and slow LNLTs on two separate days. The caloric density of the nutrient was 1kcal/ml. The TVDRI and MVDRI were recorded, and the corresponding TVPS and MVPS were measured by B-ultrasound. Results: (1) There were positive correlations between TVDRI and TVPS , and between MVDRI and MVPS in both slow and rapid LNLTs. (2) TVDRI and MVPS in slow LNLT were significantly smaller than those in rapid LNLT, but MVDRI was significantly larger in slow LNLT than that in rapid LNLT. (3) TVDRI was much closer to TVPS in slow LNLT than those in rapid LNLT. But MVDRI was much closer to MVPS in rapid LNLT than those in slow LNLT. Conclusions: Both slow and rapid * 通讯作者 LNLTs could be used to evaluate the accommodation to a meal and visceral sensitivity of the proximal stomach. The visceral sensitivity is related to the accommodation function. TVDRI of slow LNLT is more sensitive in estimating the visceral sensitivity of the proximal stomach; MVDRI of rapid LNLT is more accurate in estimating the accommodation of the proximal stomach.