Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (9): 1433-1437.doi: 10.16352/j.issn.1001-6325.2022.09.1433

• Mini Reviews • Previous Articles     Next Articles

Progress in the treatment with dopamine receptor agonist-induced impulse control disorders

ZHANG Rui, WU Xue-yan*   

  1. Department of Endocrinology, Key laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730, China
  • Received:2021-07-12 Revised:2022-02-24 Online:2022-09-05 Published:2022-09-02

Abstract: It is found that patients with hyperprolactinemia may have impulse control disorder(ICD) when treated with dopamine receptor agonist(DA), such as pathological gambling, high sexual desire, high appetite and forced shopping. This phenomenon also occurs in patients with Parkinson's disease (PD) or other neurological diseases treated with dopamine agonists. The pathogenesis may be that DA overstimulates D3 receptor. Drug withdrawal is a well accepted treatment method, which may reach a better catabatic outcome.

Key words: impulse control disorder, dopamine receptor agonist, hyperprolactinemia

CLC Number: