Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (7): 1139-1143.doi: 10.16352/j.issn.1001-6325.2022.07.1139

• Mini Reviews • Previous Articles     Next Articles

Application of single-cell RNA sequencing technologies in aortic dilatation diseases

ZHENG Kai, REN Hua-liang, ZHANG Wang-de, LI Chun-min*   

  1. Department of Vascular Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020,China
  • Received:2021-08-26 Revised:2022-01-07 Online:2022-07-05 Published:2022-06-29
  • Contact: *

Abstract: Aortic dilation disease, represented by aortic dissection and aortic aneurysm, is the most dangerous disease in vascular surgery. The pathogenesis of this disease is not very clear. Single-cell RNA sequencing (scRNA-seq) technology can study cell heterogeneity and identify new cell states and populations at the single cell level, which provides a new tool for studying the occurrence and development mechanism of aortic disease.

Key words: aortic disease, single-cell RNA sequencing, single-cell transcriptome sequencing, high throughput RNA sequencing

CLC Number: