Abstract: The construction of a professional learning management system(LMS)platform is one of the important tasks in modern medical education reform. Peking Union Medical College (PUMC) had built the LMS based on open-source software modular object-oriented dynamic learning environment(Moodle)that supports the implementation of blended teaching methods. First, a teaching model for performing blended teaching effectively based on Moodle was built. Under the guidance of such model, the autonomous learning environment was established, which provided orderly, abundant and various learning resources for 46 medicine related courses in PUMC. In such a virtual environment, the students' self-directed learning could guided, supervised and provided feedback. The teachers could combine the virtual learning environment with classroom teaching closely, and develop more innovative and exploratory teaching activities. Furthermore, the data from whole learning process could be accumulated by Moodle easily to evaluate the teaching quality. Through Moodle, modern teaching methods could be applied in the medical education in PUMC effectively and efficiently.

Key words: Moodle, blended teaching, autonomous learning, medical education reform