Basic & Clinical Medicine ›› 2018, Vol. 38 ›› Issue (10): 1457-1460.

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Advances in glymphatic system and cognitive impairment related diseases

Qian ZHOU1,Hao 无LI   

  • Received:2017-12-22 Revised:2018-03-29 Online:2018-10-05 Published:2018-09-28
  • Contact: Hao 无LI

Abstract: The glympahtic system rapidly removes metabolic waste in the brain through the drainage and material exchange between cerebrospinal fluid and interstitial fluid. The influencing factors include AQP-4, cerebral artery pulse, sleep and body posture. Glympahtic system dysfunction can lead to a variety of diseases related to cognitive impairment. Glymphatic system function recovery may be a new way to prevent and treat diseases related to cognitive impairment.

Key words: glymphatic system, paravascular space, cognitive impairment

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