Basic & Clinical Medicine ›› 2016, Vol. 36 ›› Issue (9): 1285-1289.

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Research progress on phenotype transition and efferocytosis of macrophages in chronic skin ulcer


  • Received:2015-09-21 Revised:2015-12-04 Online:2016-09-05 Published:2016-08-30
  • Contact: Ping LI

Abstract: Macrophages play a central role in all stages of wound healing and orchestrate the wound healing process. Efferocytosis and phenotype transition are not two independent biological processes, but have the connection and necessary relationship. The phagocytosis of neutrophils influences macrophage phenotype, causing the chronic inflammation.

Key words: Key words: Chronic skin ulcer, Macrophage, efferocytosis, phenotype transition