Abstract: Objective To assess the efficacy and safety of endoscopic submueosal dissection (ESD) for early gastric cancer (EGC). Methods Retrospectively analysis 33 patients with early gastric cancer treated by ESD in Digestive Endoscopy Center of Beijing Military General Hospital from June 2012 to June 2013. Data collected including age, gender, tumor size, tumor location, macroscopic type, histology, nonlifting sign, procedure time and complications. Results The enbloc resection rate was 97% (32/33) and the R0 resection rate was 93.9% (31/33). The rate of immediate perforation was 3.03% (1/33), bleeding was 18.2% (6/33), no postoperative bleeding and delayed perforation was recorded. Tumor location (P＜0.05) and macroscopic type (P＜0.05) were associated with complications. Tumor size (P＜0.05), tumor location (P＜0.05) and nonlifting sign (P＜0.05) were associated with operative time. Conclusion ESD is an applicable method for early gastric cancer with high rate of en bloc resection and complete resection.

Key words: Endoscopic submucosal dissection, Early Gastric Cancer, complication, safety