Application of iPSC technique in disease modeling

Basic & Clinical Medicine ›› 2013, Vol. 33 ›› Issue (12): 1626-1629.

Application of iPSC technique in disease modeling

Wen-bo liu¹,XIN FURan XIAO

Received:2013-01-24 Revised:2013-03-27 Online:2013-12-05 Published:2013-11-28
Contact: Ran XIAO E-mail:xiaoran@pumc.edu.cn

Abstract: The procedure of employing induced pluripotent stem cell (iPSC) technology for in vitro disease modeling is as follow: 1) generation of patient-specific iPSCs; 2) characterization of iPSCs; 3) differentiation of iPSCs into disease-relevant subtypes; 4) utilization of iPSCs and subtypes to recapitulate features and development of the original disease; 5) pharmacological interventions.

Key words: induced pluripotent stem cell, disease modeling

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Wen-bo liu XIN FU Ran XIAO. Application of iPSC technique in disease modeling[J]. Basic & Clinical Medicine, 2013, 33(12): 1626-1629.

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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2013/V33/I12/1626

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