Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (7): 1148-1151.doi: 10.16352/j.issn.1001-6325.2022.07.1148

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Progress on the role of melatonin in dilated cardiomyopathy

LIU Jia1, XU Kai2, SHI Rui-zheng1, ZHANG Guo-gang2*   

  1. 1. Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha 410008;
    2. Department of Cardiovascular Medicine, the Third Xiangya Hospital, Central South University, Changsha 410013, China
  • Received:2021-02-09 Revised:2021-06-15 Online:2022-07-05 Published:2022-06-29
  • Contact: *

Abstract: Dilated cardiomyopathy (DCM) is characterized by decreased systolic function and left or biventricular enlargement. There is no single specific medicine to delay the progression of DCM. Melatonin (Mel) plays a key role in many cardiovascular diseases by regulating cell damage, oxidative stress and other pathological processes,delaying myocardial remodeling and protecting cardiac function. There is a close relationship between DCM and Mel. It is confirmed that Mel plays an important role in delaying the progression of DCM.

Key words: melatonin, dilated cardiomyopathy, cardioprotective effect

CLC Number: