Abstract: Objective To isolate and identify Rhodococcus equi(R.equi) from clinical specimens for potential relationship between antibiotic sensitivity and efficacy of antibiotic chemotherapy. Methods From April 2019 to April 2020, 17 cases patients with positive isolation of R. equi were grouped as test one and and 17 cases of patients underwent empirical treatment only were collected as the control group. Results The efficacy of antibiotic chemotherapy with sensitivity test (test group) showed significantly better than that of the control group. Conclusions Rational use of antibiotics chemotherapy supported by sensitivity test can significantly improve the effect of chemotherapy.

Key words: isolation and identification, Rhodococcus equi, antibiotic sensitivity, clinical curative effect