Basic & Clinical Medicine ›› 2021, Vol. 41 ›› Issue (7): 1052-1055.

• Mini Reviews • Previous Articles     Next Articles

Research progress of inflammatory response of adipose tissue

SHU Feng, WANG Meng-yi, ZHANG Shi-wu, LI Qian-zhu, ZHANG Wei-hua*   

  1. Department of Pathophysiology, Harbin Medical University, Harbin 150080, China
  • Received:2020-07-06 Revised:2020-10-10 Online:2021-07-05 Published:2021-06-17
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Abstract: This review reported lipid mediators associated with inflammatory responses in adipose tissue, pro-inflammatory mediators: eicosane compounds derived from cyclooxy-genase (e.g. prostaglandins); Pro-resolving mediators: lipoxins produced by omega-6 polyunsaturated fatty acids, and resolvins produced by omega-3 polyunsaturated fatty acids. The treatment of inflammatory responses should not be limited to the use of acute cascade antagonists or inhibitors, but should be expanded to take into account the great therapeutic potential of inducers or agonists in the inflammatory resolution phase.

Key words: obesity, adipose tissue, acute inflammatory response, resolution

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