Abstract: Objective To explore the clinical value of fiberoptic ductoscopy in the diagnosis and treatment of pathological nipple discharge. Methods A total of 313 patients with pathological nipple discharge from October 2018 to June 2019 in the Breast Surgery Department of Tongzhou Maternal ＆ Child Health Hospital, Beijing were retrospectively reviewed. Results Fiberoptic ductoscopy was performed in 313 patients with pathological nipple discharge, 124 cases were space occupying lesions and underwent surgical operation. Postoperative pathology confirmed 6 cases of ductal carcinoma in situ, 1 case of lobular carcinoma in situ, 5 cases of atypical hyperplasia, 5 cases of intraductal papillomatosis, 6 cases of multiple intraductal papilloma, 38 cases of intraductal papilloma, 4 cases of fibroadenoma, 9 cases of breast adenosis and 50 cases of hyperplasia of mammary glands. Conclusions Fiberoptic ductoscopy can directly diagnose the etiology of pathological nipple discharge. The guide wire localization surgery guided by fiberoptic ductoscopy can more accurately remove the intraductal lesions, and fiberoptic ductoscopy can detect early breast cancer by nipple discharge.

Key words: intraductal papilloma, nipple discharge, fiberoptic ductoscopy