Basic & Clinical Medicine ›› 2021, Vol. 41 ›› Issue (2): 178-183.

• Original Articles • Previous Articles     Next Articles

Goal-directed fluid therapy optimizes hemodynamics on the elderly patients undergoing lumbar decompressive surgery and reduces postoperative complications

XIA Di, XU Li*, LI Xu, HUANG Yu-guang   

  1. Department of Anesthesiology,Peking Union Medical College Hospital,CAMS & PUMC,Beijing 100730,China
  • Received:2020-08-23 Revised:2020-12-19 Online:2021-02-05 Published:2021-01-19
  • Contact: *

Abstract: Objective To explore the impact of goal-directed fluid therapy(GDT) management strategy on the perioperative complications of elderly patients undergoing lumbar spine surgery. Methods Elderly patients undergoing elective lumbar spine surgery were selected and randomly divided into the control group with routine fluid management according to the existing anesthetic fluid treatment standards and the experimental group for intraoperative fluid management using GDT strategies. Hemodynamic indicators, perioperative fluid, gastrointestinal function indicators and the incidence of complications in the 30 days after surgery were collected. Results Cardiac output (CO) and cardiac index (CI) of the experimental group were significantly higher than those of the control group (P<0.05) at the end of operation. The two groups also showed a significant different(P<0.05) in total intraoperative fluid infusion volume, which was more significant than comoparison with experimental(GDT)group. However,the dosage of vasoactive drugs was significantly lower in the observation group (P<0.05). Compared with the observation group, the number of patients receiving medicine-assisted defecation and exhaust was significantly less than that in the experimental group (P<0.05). Compared with the observation group, the experimental group has significantly less was complication infectio (P<0.05). Conclusions GDT can reduce postoperative complications in elderly patients undergoing lumbar spine surgery, thereby improving the perfusion and prognosis.

Key words: goal-directed fluid therapy, lactate acid, perfusion, infection

CLC Number: