Abstract: Objective To evaluate the correlation of age of onset, course of stone with renal function among urinary stone patients. Methods Totally 183 patients' history data were reviewed, including age of onset for stone, course of stone and eGFR. We evaluated correlation of age of onset, course of stone with eGFR by multivariate linear regression, to find potential relationship of urinary stone with renal function damage. Results With higher level of renal function, mean course of stone was longer among urinary stone patients. Meanwhile, among patients with renal function at 1-3 level, mean age of onset also increased as level of renal function increasing. Furthermore, multivariate linear regression revealed that age of onset, course of stone and eGFR were in linear correlation. Conclusions With older age of onset for stone and/or longer course of stone, patients' renal function is impaired more seriously with lower eGFR among urinary stone patients.

Key words: urinary stone, age of onset, course of disease, renal function