Abstract: In the microenvironment of pancreatic cancer, exosomes derived from different cell promote the growth, migration and invasion of pancreatic cancer by transferring RNA and other substances, while promoting the generation of gemcitabine resistance in pancreatic cancer. Exosomes carry a lot of information about pancreatic cancer. We can early diagnose pancreatic cancer by capturing exosomes from body fluids and analyzing their contents. Using chip technology can make detection easier and faster. One of the potential treatments for pancreatic cancer is blocking the production and transmission of exosomes or transporting antineoplastic drugs with exosomes.

Key words: exosomes, pancreatic neoplasms