Basic & Clinical Medicine ›› 2018, Vol. 38 ›› Issue (3): 405-408.

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Advances in research on anti-Mullerian tube hormone and male reproductive endocrine-related diseases


  • Received:2017-01-17 Revised:2017-04-26 Online:2018-03-05 Published:2018-02-27

Abstract: Anti-Müllerian tube (AMH) hormone, also known as Müllerian inhibitory substances, is a member of the transformation system. In men, AMH, is secreted by immature Sertoli cell, promotes the degradation of male fetal Müllerian tubes, and participates in testicular development and spermatogenesis. AMH can affect gonadotropin-releasing hormone (GnRH), pituitary secretion of follicle stimulating hormone (FSH), luteinizing hormone (LH) and testicular stromal cells secrete testosterone (T), inhibin B, and thus by affecting the hypothalamus- pituitary - gonadal axis (HPG axis) causes male reproductive endocrine related diseases.

Key words: Key words: AMH, HPG axis, Spermatogenesis disturbance, Spermatogenesis