Abstract: Induced pluripotent stem cell is a landmark in the stem cell study field, which has developed rapidly in the past 10 years. By obtaining induced pluripotent stem cells from somatic cell, and then differentiating into cardiomyocyte, various cardiomyocyte disease models could be established，which can be used for research of disease mechanisms, drug screening and gene therapy. This review introduces the successfully established cardiomyocyte disease models from human induced pluripotent stem cells, and points out the problems and prospects.

Key words: induced pluripotent stem cell, cardiomyocyte disease model, research progress