Abstract: Object To investigate the effects of CBL in teaching human embryology for medical students. Methods After having seminar with clinical case, scoring rate of questions discussed and not discussed in final exam were compared in recent 3 years. Embryological knowledge were evaluated in 1, 2, 3 years after embryology class by online test. Results There was no difference of total scoring rate among 3 grades in final exam, while questions discussed was higher significantly than those not discussed（p<0.01）. Scoring rate of objective questions discussed was higher significantly than those not discussed. Scoring rate of online test decreased with years after embryology class, while questions discussed were better than not discussed. Conclusions Seminar with clinical case as CBL could improve the learning outcomes of embryology in short and long term memory.

Key words: Case based learning, Embryology