Basic & Clinical Medicine ›› 2017, Vol. 37 ›› Issue (11): 1629-1633.
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Abstract: Sodium-dependent phosphate cotransporter is encoded by the solute carrier family 17 gene. The gene is located on chromosome 6 and is an important transporter of the organic anion as the substrate and is expressed in kidney and other tissues.Among them, the sodium-dependent phosphate transporter type 1, 3, and 4 have the function of transferring uric acid, and abnormal function can lead to the decrease of uric acid excretion, which can cause hyperuricemia and even induce gout.
Key words: uric acid, hyperuricemia, gout, sodium-dependent phosphate cotransporter, genetic polymorphism
CLC Number:
R589.7
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2017/V37/I11/1629