Abstract: The latest study that long non-coding RNAs(lncRNA), regarded as a new class of non-coding gene regulators, can regulate gene expression in 3 aspects. The changes of the hereditary material can affect lncRNA gene expression and lncRNA may contribute to the proliferation and apoptosis, the invasiveness and differentiation of glioma cells, and to angiogenesis. LncRNA can serve as novel biomarkers and therapeutic targets to help diagnose and treat gliomas.

Key words: Long non-coding RNA, glioma